2-Bromopropane → HCID 56630726, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 0.9 g (0.0042 moles) of 3-(1H-tetrazol-5-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidine, 25 ml of dimethylformamide, 1.15 g (0.0084 moles) of anhydrous potassium carbonate and 1.1 ml (0.0126 moles) of isopropyl bromide was stirred at 90° C. for 1 hour. The hot yellow solution was filtered, the filtrate evaporated. To the crystalline residue 25 ml of water was added, and the crystals were collected. 0.6 g (55.8%) of the title compound was obtained, in the form of white crystals, m.p.: 146°-148° C.

Provenance & Evidence