Zinc → HCID 178497614, compound

HRID 2259598Notes

Reaction equation

HRID 2259598 reaction equation
[Zn:1].[CH3:2][O:3][C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[C:12]1[CH:17]=[CH:16][C:15]([CH2:18][Br:19])=[CH:14][CH:13]=1)=[O:5]>O1CCCC1>[Br-:19].[CH3:2][O:3][C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[C:12]1[CH:17]=[CH:16][C:15]([CH2:18][Zn+:1])=[CH:14][CH:13]=1)=[O:5]

Participants

4

Reactant 2

HCID 23994ZincHCID 11012181Methyl 4'-(bromomethyl)biphenyl-2-carboxylate

Product 1

HCID 178497614HCID 178497614, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent2×

Procedure

Using the procedure of Example 1,800 mg of electrolytic zinc, 2 ml of anhydrous tetrahydrofuran and 3.05 g of [(2'-(methoxycarbonyl)-(1,1'-biphenyl)-4-yl)-methyl]-bromide in 12 ml of anhydrous tetrahydrofuran were reacted.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-bd849c998509497abf761258ce67fc1d
Source dataset
uspto-grants-1995_12
Patent number
US05474996

Reaction notes

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