HCID 15342517, compound → HCID 19001539, compound

Participants

Reaction Conditions

Reaction Steps

3.48 g of the 3-[2-(5-oxotetrahydrofuran-2-yl)-benzothiazol-6-yl]-5-methoxymethyl-2-oxazolidinone obtained in the Example 5 was dissolved in 20 ml of anhydrous tetrahydrofuran and the solution was cooled to -50° C. 30 ml of a 1.0M solution of diisobutylaluminum hydride in tetrahydrofuran was added dropwise thereto. After stirring for 30 min followed by ordinary treatment and recrystallization, 2.8 g of 3-[2-(1,4-dihydroxybutyl)benzothiazol-6-yl]-5-methoxymethyl-2-oxazolidinone was obtained.

Provenance & Evidence