huagongshe.com
HRID225969

反应详情

EQUATION

反应方程式

HRID 225969 的结构方程式

REACTANTS

反应物

2
结构：C1COCCN1
HCID8083

Morpholine

C4H9NO

结构：CON=C1C[C@@H](CCC(=O)O)N(C(=O)c2ccc(-c3ccccc3)cc2)C1
HCID131727528

未命名化合物

2 次

PRODUCTS

生成物

1
结构：CON=C1C[C@@H](CCC(=O)N2CCOCC2)N(C(=O)c2ccc(-c3ccccc3)cc2)C1
HCID131727531

未命名化合物

收率 97%

PROCEDURE

实验过程

The same method as employed in the preparation of Example 7, but starting from 3-[(2R,4EZ)-1-(biphenyl-4-ylcarbonyl)-4-(methoxyimino)pyrrolidin-2-yl]propanoic acid (Intermediate 8) and morpholine, gave the title compound. Yield: 97%. HPLC purity: 96%

WORKUP

后处理

  1. customThe same method as employed in the preparation of Example 7