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HRID22598

反应详情

EQUATION

反应方程式

HRID 22598 的结构方程式

REACTANTS

反应物

2
结构：CCOC(C)=O
HCID8857

Ethyl acetate

C4H8O2

结构：Clc1ccc2ccc(C3CC3c3cccc(C4OCCO4)c3)nc2c1
HCID10405721

未命名化合物

PRODUCTS

生成物

1
结构：O=Cc1cccc(C2CC2c2ccc3ccc(Cl)cc3n2)c1
HCID10447962

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1CCOC1.CC(=O)O.O
溶剂HCID21877175

未命名化合物

PROCEDURE

实验过程

The dioxolane (step 3) (500 mg, 1.42 mmoles) was heated at reflux in 9 mL of THF:AcOH:H2O 6:2:1 for 2 hours. Addition of 25% NH4OAc, extraction with EtOAc, drying, evaporation, and flash chromatography on silica with EtOAc:toluene 2.5:97.5 afforded the title compound.

WORKUP

后处理

  1. customdrying
  2. customevaporation, and flash chromatography on silica with EtOAc:toluene 2.5:97.5