Dichloromethane → HCID 67714441, compound

HRID 2259893Notes

Reaction equation

HRID 2259893 reaction equation
[NH2:1][CH2:2][C:3]1[C:12]2[O:11][C:10]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)=[C:9]([CH3:19])[C:8](=[O:20])[C:7]=2[CH:6]=[CH:5][CH:4]=1.ClCCS(Cl)(=O)=[O:25].Cl[CH2:29][Cl:30].[CH2:31]([N:33]([CH2:36]C)CC)C>>[Cl:30][CH2:29][CH2:31][NH:33][C:36](=[O:25])[NH:1][CH2:2][C:3]1[C:12]2[O:11][C:10]([C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=3)=[C:9]([CH3:19])[C:8](=[O:20])[C:7]=2[CH:6]=[CH:5][CH:4]=1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 15385Ethanesulfonylchloride, 2-chloro-HCID 19972800HCID 19972800, compound

Product 1

HCID 67714441HCID 67714441, compound

Procedure

This compound can be prepared by reacting Intermediate XXIV with 2-chloroethylsulfonylchloride in an halogenated solvent (e.g., dichloromethane) in presence of triethylamine at 0°-40° C., according to A. A. Goldberg, Jr., J. Chem. Soc., 464 (1945).

Workup

  1. customThis compound can be prepared
  2. customat 0°-40° C.

Sources & evidence

ORD record
ord-946a9812f60c4b45b732e3676929913a
Source dataset
uspto-grants-1995_12
Patent number
US05474994

Reaction notes

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