HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-trichloromethylpyridine → 2-Chloro-5-(chloromethyl)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-trichloromethylpyridine | HCID 50293 | — |
| Catalyst | Zinc | HCID 23994 | — |
| Product | 2-Chloro-5-(chloromethyl)pyridine | HCID 155479 | — |
Reaction Steps
The method according to claim 1, wherein 2-chloro-5-trichloromethylpyridine is reduced at a reaction temperature of from -20° C. to +100° C. with from 2 to 15 equivalents of the proton donor and from 2 to 15 equivalents of zinc, relative to 1 mol of 2-chloro-5-trichloromethylpyridine and from 0.5 to 50 parts by weight of the solvent, relative to 1 mol of 2-chloro-5-trichloromethylpyridine, to obtain 2-chloro-5-chloromethylpyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05475112 |
| Source dataset | uspto-grants-1995_12 |
| ORD ID | ord-49b40a89e2b7492eb5459bfe2ca97c83 |
| Source note | uspto-grants-1995_12 |