Glycidol → 1,2-Propanediol, 3-(dodecylamino)-

HRID 2260081Notes

Reaction equation

HRID 2260081 reaction equation
[CH2:1]([NH2:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[CH2:14]1[O:16][CH:15]1[CH2:17][OH:18]>>[OH:16][CH:15]([CH2:17][OH:18])[CH2:14][NH:13][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

Participants

3

Reactant 2

HCID 11164GlycidolHCID 13583Dodecylamine

Product 1

HCID 1024961,2-Propanediol, 3-(dodecylamino)-

Procedure

Dodecylamine (25.02 g, 0.13 mole) was heated to 85° C. Glycidol (10 g, 0.13 mole) was added dropwise. The reaction solution was heated under nitrogen for 3 hours and was stirred overnight at room temperature. A white solid was obtained (crude yield=33.27 g). The solid was recrystalized from hot hexane (crystallized 10.86 g).

Workup

  1. temperatureThe reaction solution was heated under nitrogen for 3 hours
  2. customA white solid was obtained (crude yield=33.27 g)
  3. customThe solid was recrystalized from hot hexane (crystallized 10.86 g)

Sources & evidence

ORD record
ord-1154cc03e7904ae0a02dac36e85a2e70
Source dataset
uspto-grants-1995_12
Patent number
US05476671

Reaction notes

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