Glycidol → 3-(Tetradecylamino)propane-1,2-diol

Participants

Reaction Steps

Tetradecylamine (28.80 g, 0.13 mole) was heated to 85° C. Glycidol (10.00 g, 0.13 mole) was added dropwise. The reaction solution was heated under nitrogen for 3 hours and then was stirred overnight at room temperature. A white solid was obtained (crude yield=38.45 g). The solid was recrystalized from hot hexane (yield=12.2 g).

Provenance & Evidence