HRID2260087

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8181

Methyl hexadecanoate

C17H34O2

HCID14797

Potassium hydroxide

HKO

HCID111007

3-(Hexadecylamino)propane-1,2-diol

C19H41NO2

PRODUCTS

生成物

结构：CCCCCCCCCCCCCCCCN(CC(O)CO)C(=O)CCCCCCCCCCCCCCC

HCID15825474

未命名化合物

PROCEDURE

实验过程

N-(2,3-dihydroxypropyl)-N-hexadecylamine (0.40 g, 0.0013 mole) and potassium hydroxide (0.01 g, 0.18 mmole) were heated to 85° C. under vacuum. Methyl palmitate (0.343 g, 0.0013 mole) was heated to melt and added dropwise to the reaction. The reaction was heated under vacuum for 6 hours. A waxy off-white solid was obtained. The waxy solid was recrystalized from hot hexane (yield=0.4 g).

WORKUP

后处理

additionadded dropwise to the reaction
temperatureThe reaction was heated under vacuum for 6 hours
customA waxy off-white solid was obtained
customThe waxy solid was recrystalized from hot hexane (yield=0.4 g)

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-f73249bdb3a74b9a820d288babe2b712
来源数据集: uspto-grants-1995_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05476671
来源说明: uspto-grants-1995_12

反应 SMILES

[OH:1][CH:2]([CH2:21][OH:22])[CH2:3][NH:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20].[OH-].[K+].[C:25]([O:42]C)(=O)[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH3:40]>>[OH:1][CH:2]([CH2:21][OH:22])[CH2:3][N:4]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[C:25](=[O:42])[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH3:40]