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HRID2260389

反应详情

EQUATION

反应方程式

HRID 2260389 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)N1[C@@H](c2ccccc2)[C@H](C(=O)O)OC1(C)C
HCID10969286

(4S,5R)-3-(tert-Butoxycarbonyl)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-5-carboxylic acid

C17H23NO5

结构：CCOC(=O)[C@@H]1OC(CC)(CC)N(C(=O)OC(C)(C)C)[C@H]1c1ccccc1
HCID54436966

未命名化合物

PRODUCTS

生成物

1
结构：CCC1(CC)O[C@@H](C(=O)O)[C@H](c2ccccc2)N1C(=O)OC(C)(C)C
HCID54422886

未命名化合物

收率 79.8%

PROCEDURE

实验过程

(4S,5R)-3-tert-Butoxycarbonyl-2,2-diethyl-4-phenyl-5-oxazolidinecarboxylic acid may be obtained under the conditions described in Example 6 for the preparation of (4S,5R)-3-tert-butoxycarbonyl-2,2-dimethyl-4-phenyl-5-oxazolidinecarboxylic acid. Thus, starting with 2.3 g of ethyl (4S,5R)-3-tert-butoxycarbonyl-2,2-diethyl-4-phenyl-5-oxazolidinecarboxylate, 1.7 g of (4S,5R)-3-tert-butoxycarbonyl-2,2-diethyl-4-phenyl-5-oxazolidinecarboxylic acid is obtained in the form of white crystals, melting point 185° C.