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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2260389Generated: November 1, 2026

(4S,5R)-3-(tert-Butoxycarbonyl)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-5-carboxylic acid → HCID 54422886, compound

https://huagongshe.com/reaction/2260389

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4S,5R)-3-(tert-Butoxycarbonyl)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-5-carboxylic acidHCID 10969286—
ReactantHCID 54436966HCID 54436966—
ProductHCID 54422886HCID 5442288679.8%

Reaction Steps

(4S,5R)-3-tert-Butoxycarbonyl-2,2-diethyl-4-phenyl-5-oxazolidinecarboxylic acid may be obtained under the conditions described in Example 6 for the preparation of (4S,5R)-3-tert-butoxycarbonyl-2,2-dimethyl-4-phenyl-5-oxazolidinecarboxylic acid. Thus, starting with 2.3 g of ethyl (4S,5R)-3-tert-butoxycarbonyl-2,2-diethyl-4-phenyl-5-oxazolidinecarboxylate, 1.7 g of (4S,5R)-3-tert-butoxycarbonyl-2,2-diethyl-4-phenyl-5-oxazolidinecarboxylic acid is obtained in the form of white crystals, melting point 185° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05476954
Source datasetuspto-grants-1995_12
ORD IDord-45d52ba0e02a4a159994600b5513d0eb
Source noteuspto-grants-1995_12