Isopropanol → N-[(3S)-Tetrahydro-2,5-dioxo-3-furanyl]formamide

HRID 2260417Notes

Reaction equation

[NH2:1][C@H:2]([C:7]([OH:9])=[O:8])[CH2:3][C:4]([OH:6])=O.[CH:10]([OH:13])(C)C>>[CH:10]([NH:1][C@@H:2]1[C:7](=[O:8])[O:9][C:4](=[O:6])[CH2:3]1)=[O:13]

Participants

Reactant 2

HCID 3776Isopropanol

HCID 5960L-Aspartic Acid

Product 1

HCID 11298025N-[(3S)-Tetrahydro-2,5-dioxo-3-furanyl]formamide

Procedure

formylating L-aspartic acid in a first reaction mixture of formic acid, acetic anhydride and isopropyl alcohol to yield N-formyl aspartic anhydride;

Sources & evidence

ORD record: ord-5ce2f950670a4ae29332ba52551b3fa7
Source dataset: uspto-grants-1995_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05476961

Reaction notes

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