Ethanol → HCID 22600667, compound

HRID 2260463Notes

Reaction equation

HRID 2260463 reaction equation
C(O)C.[Cl-].[NH4+].[CH3:6][S:7][C:8]1[CH:13]=[CH:12][C:11]([N+:14]([O-])=O)=[CH:10][C:9]=1[OH:17]>[Zn].O>[CH3:6][S:7][C:8]1[CH:13]=[CH:12][C:11]([NH2:14])=[CH:10][C:9]=1[OH:17]

Participants

6

Reactant 3

HCID 702EthanolHCID 25517Ammonium ChlorideHCID 18997705HCID 18997705, compound

Product 1

HCID 22600667HCID 22600667, compound

Reagents, catalysts & solvents 2

HCID 23994ZincCatalystHCID 962WaterSolvent

Procedure

The suspension obtained on mixing 150 ml of 96° strength ethanol, 16 ml of water, 2.3 g of ammonium chloride and 78 g of finely powdered zinc is brought to reflux. 25.1 g (0.15 mol) of 2-methylthio-5-nitrophenol are added portionwise so as to maintain the reflux without heating (exothermic reaction).

Workup

  1. customThe suspension obtained
  2. temperatureto reflux
  3. temperatureto maintain the
  4. temperaturereflux
  5. temperaturewithout heating
  6. custom(exothermic reaction)

Sources & evidence

ORD record
ord-0270df3376064a2eaafaf9ff24fb5efd
Source dataset
uspto-grants-1995_12
Patent number
US05478359

Reaction notes

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