反应详情

Using an analogous procedure to that described in Example 1 except that a catalytic amount (0.01 g) of potassium iodide was added, 6-mercapto-1-methyl-1,2,3,4-tetrahydroquinolin-2-one was reacted with 4-(2-chlorothiazol-5-yl)-4-methoxy-2,2-dimethyltetrahydropyran to give 4-methoxy-2,2-dimethyl-4-[2-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-ylthio)thiazol-5-yl]tetrahydropyran in 80% yield as a foam;

1. additionwas added