HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexane → HCID 131719232, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexane | HCID 8058 | — |
| Reactant | 1,2,3,4-Tetrahydroquinoline-1-carbonyl chloride | HCID 13591069 | — |
| Reactant | 4-(6-fluoro-1-methyl-1H-indazol-3-yl)-1-(3-hydroxypropyl)piperidine | HCID 18998799 | — |
| Product | HCID 131719232 | HCID 131719232 | 9% |
Reaction Steps
Starting from 4-(6-fluoro-1-methyl-I H-indazol-3-yl)-1-(3-hydroxypropyl)piperidine (370 mg; 1.2 mmol), 3M N-butyl lithium in hexane (0.7 ml; 2.1 mmol) and 1,2,3,4-tetrahydroquinolin-1-carbonyl chloride (300 mg; 1.5 mmol) using the procedure described in example 7 was prepared 50 mg (9%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05478845 |
| Source dataset | uspto-grants-1995_12 |
| ORD ID | ord-31343d9265cc4db2b44015268aeeb1b4 |
| Source note | uspto-grants-1995_12 |