5H-[1,3]dioxolo[4,5-f]indole → HCID 12369276, compound

HRID 2260646Notes

Reaction equation

HRID 2260646 reaction equation
[CH2:1]1[O:12][C:11]2[CH:10]=[C:9]3[C:5]([CH:6]=[CH:7][NH:8]3)=[CH:4][C:3]=2[O:2]1>C(O)(=O)C>[CH2:1]1[O:12][C:11]2[CH:10]=[C:9]3[C:5]([CH2:6][CH2:7][NH:8]3)=[CH:4][C:3]=2[O:2]1

Participants

3

Reactant 1

HCID 2607975H-[1,3]dioxolo[4,5-f]indole

Product 1

HCID 12369276HCID 12369276, compoundYield 42.1%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

5,6-methylenedioxyindole (1.3 g, 8 mmol) dissolved in 25 ml glacial acetic acid was reduced catalytically (1 atm., 22° C.) using 370 mg PtO2 hydrate to give 550 mg of crude 2,3-dihydro-5,6-methylenedioxyindole which was used without further purification.

Workup

  1. custom(1 atm., 22° C.)

Sources & evidence

ORD record
ord-8205f5b58f0d4888ac07ad44c2f92e72
Source dataset
uspto-grants-1995_12
Patent number
US05478845

Reaction notes

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