Succinic Acid → L-Aspartic Acid

Participants

Reaction Conditions

Reaction Steps

Monoammonium maleate (3.00 g of 94% wet salt, 0.0212 mole) and succinic acid (0,278 g, 0.0024 mole) were thoroughly mixed together and then were reacted as in Example 2 and 3 by heating in a convection oven at 230°240° C. for 40 minutes. A brittle, red-brown solid was obtained which weighed 2,204 g. Hydrolysis of this product with sodium hydroxide produced an aspartic acid copolymer having molecular weights by GPC of Mw 1717, Mn 1016, Mw/Mn 1.69.

Provenance & Evidence