Hydrochloric Acid → HCID 67784141, compound

HRID 2260804Notes

Reaction equation

HRID 2260804 reaction equation
C(OC([N:8]1[CH2:13][C@H:12]2[CH2:14][C@@H:9]1[CH2:10][N:11]2[C:15]1[CH:20]=[N:19][CH:18]=[CH:17][N:16]=1)=O)(C)(C)C.[ClH:21]>>[ClH:21].[N:16]1[CH:17]=[CH:18][N:19]=[CH:20][C:15]=1[N:11]1[CH2:10][C@H:9]2[CH2:14][C@@H:12]1[CH2:13][NH:8]2

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 15813425HCID 15813425, compound

Product 1

HCID 67784141HCID 67784141, compound

Procedure

A solution of 3.2 g of product from Example 3 and 58 ml of 1N methanolic hydrogen chloride is stirred at room temperature overnight. The reaction is concentrated in vacuo to dryness, diluted with isopropyl alcohol and reconcentrated in vacuo to dryness. The residue is recrystallized from a mixture of isopropanol/diethyl ether to give 2.1 g of the desired product as pale yellow crystals:

Workup

  1. concentrationThe reaction is concentrated in vacuo to dryness
  2. additiondiluted with isopropyl alcohol
  3. customThe residue is recrystallized from a mixture of isopropanol/diethyl ether

Sources & evidence

ORD record
ord-ad716d294d0e40e1bf53f9be6b5a2d26
Source dataset
uspto-grants-1995_12
Patent number
US05478939

Reaction notes

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