HCID 22098195, compound → HCID 22098497, compound

HRID 2260866Notes

Reaction equation

HRID 2260866 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][C:12]([N:15]3[CH2:19][CH2:18][N:17]([CH2:20][CH2:21][C:22]([O:24][CH3:25])=[O:23])[C:16]3=[O:26])=[C:11]([N+:27]([O-])=O)[CH:10]=2)=[CH:5][CH:4]=1)#[N:2].[H][H]>C(OCC)(=O)C.[Pd]>[NH2:27][C:11]1[CH:10]=[C:9]([C:6]2[CH:5]=[CH:4][C:3]([C:1]#[N:2])=[CH:8][CH:7]=2)[CH:14]=[CH:13][C:12]=1[N:15]1[CH2:19][CH2:18][N:17]([CH2:20][CH2:21][C:22]([O:24][CH3:25])=[O:23])[C:16]1=[O:26]

Participants

5

Reactant 2

HCID 22098195HCID 22098195, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 22098497HCID 22098497, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

Prepared by reduction of 1-(4'-cyano-3-nitro-4-biphenylyl)-3-(2-methoxycarbonyl-ethyl)imidazolidin-2-one with hydrogen at 5 bars in the presence of 5% palladium/charcoal in ethyl acetate at ambient temperature.

Sources & evidence

ORD record
ord-ef746baa2d714361891bdb3b9954f547
Source dataset
uspto-grants-1995_12
Patent number
US05478942

Reaction notes

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