Acetyl chloride → HCID 22098677, compound

HRID 2260867Notes

Reaction equation

HRID 2260867 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([C:20]2[CH:25]=[CH:24][C:23]([C:26]#[N:27])=[CH:22][CH:21]=2)[CH:5]=[CH:6][C:7]=1[N:8]1[CH2:12][CH2:11][N:10]([CH2:13][CH2:14][C:15]([O:17][CH3:18])=[O:16])[C:9]1=[O:19].[C:28](Cl)(=[O:30])[CH3:29].C(N(C(C)C)C(C)C)C>C(Cl)Cl>[NH:1]([C:2]1[CH:3]=[C:4]([C:20]2[CH:21]=[CH:22][C:23]([C:26]#[N:27])=[CH:24][CH:25]=2)[CH:5]=[CH:6][C:7]=1[N:8]1[CH2:12][CH2:11][N:10]([CH2:13][CH2:14][C:15]([O:17][CH3:18])=[O:16])[C:9]1=[O:19])[C:28]([CH3:29])=[O:30]

Participants

5

Reactant 3

HCID 6367Acetyl chlorideHCID 81531DiisopropylethylamineHCID 22098497HCID 22098497, compound

Product 1

HCID 22098677HCID 22098677, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Prepared from 1-(3-amino-4'-cyano-4-biphenylyl)-3-(2-methoxycarbonyl-ethyl)-imidazolidin-2-one and acetylchloride in methylene chloride at ambient temperature using ethyl-diisopropylamine.

Sources & evidence

ORD record
ord-607271f8fea9416396b8cc9547cdf40f
Source dataset
uspto-grants-1995_12
Patent number
US05478942

Reaction notes

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