HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitrobenzaldehyde → HCID 59550635, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitrobenzaldehyde | HCID 541 | — |
| Reactant | Ethyl cyanoacetate | HCID 7764 | — |
| Reactant | Ethyl 1-acetylcyclopropane-1-carboxylate | HCID 234183 | — |
| Reactant | Ammonium Acetate | HCID 517165 | — |
| Product | HCID 59550635 | HCID 59550635 | 43.4% |
Reaction Steps
In analogy to GP 1, reaction of 28.9 g ammonium acetate (375 mmol, 8 eq.), 5 ml ethyl cyanoacetate (47.3 mmol, 1 eq.), 7.32 g 1-acetyl-cyclopropanecarboxylic acid ethyl ester (47 mmol, 1 eq.), and 7.08 g 4-nitrobenzaldehyde (47 mmol, 1 eq.) yielded 7.2 g product (43% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07846928B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-30e38d9e725645b3803d45c770a1afa8 |
| Source note | uspto-grants-2010_12 |