反应详情

In analogy to GP 1, reaction of 28.9 g ammonium acetate (375 mmol, 8 eq.), 5 ml ethyl cyanoacetate (47.3 mmol, 1 eq.), 7.32 g 1-acetyl-cyclopropanecarboxylic acid ethyl ester (47 mmol, 1 eq.), and 7.08 g 4-nitrobenzaldehyde (47 mmol, 1 eq.) yielded 7.2 g product (43% yield).