HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-(5-formyl-1-benzofuran-3-yl)prop-2-enoate → HCID 57469675, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-(5-formyl-1-benzofuran-3-yl)prop-2-enoate | HCID 71378267 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 57469675 | HCID 57469675 | 80% |
Reaction Steps
100 mg of 3-(5-Formyl-benzofuran-3-yl)-acrylic acid ethyl ester (intermediate 62) were dissolved in EtOAc in the presence of Palladium on charcoal and Argon. To this was connected a H2-balloon and hydrogenation was carried out for 12 h. The palladium was filtered off and the solvents were evaporated affording pure title compound (80 mg, 80%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07846925B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-7e535af8e49a47aa9fb79c8ee8bc9863 |
| Source note | uspto-grants-2010_12 |