Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2261208Generated: October 26, 2026

(S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine → HCID 11596637, compound

https://huagongshe.com/reaction/2261208

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidineHCID 853152—
Reactant4-(Chloromethyl)-1,3-thiazole hydrochlorideHCID 2763289—
ReactantMethyl 2,6-difluoro-4-hydroxybenzoateHCID 22087431—
ProductHCID 11596637HCID 11596637—

Reaction Steps

The title compound is prepared in a manner substantially analogous to Procedures D and E using 2,6-difluoro-4-hydroxy-benzoic acid methyl ester [CAS 194938-88-0], 4-(chloromethyl)thiazole hydrochloride [CAS 7709-58-2], and (S)(+)-1-(2-pyrrolidinylmethyl)pyrrolidine. MS (ES+) m/e 408.3

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07846950B2
Source datasetuspto-grants-2010_12
ORD IDord-24a61740a7904dfbbfd856a162c8e37c
Source noteuspto-grants-2010_12