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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2261211Generated: November 4, 2026

(S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine → HCID 11502294, compound

https://huagongshe.com/reaction/2261211

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidineHCID 853152—
Reactant4-(Chloromethyl)-2-methyl-1,3-thiazole--hydrogen chloride (1/1)HCID 2734203—
ReactantMethyl 2-fluoro-4-hydroxybenzoateHCID 22463192—
ProductHCID 11502294HCID 11502294—

Reaction Steps

The title compound is prepared in a manner substantially analogous to Procedures D and E using 2-fluoro-4-hydroxy-benzoic acid methyl ester [CAS 197507-22-5], 4-chloromethyl-2-methylthiazole hydrochloride [CAS 39238-07-8], and (S)(+)-1-(2-pyrrolidinylmethyl)pyrrolidine. MS (ES+) m/e 404.2

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07846950B2
Source datasetuspto-grants-2010_12
ORD IDord-b81920d4681e4b73a9612ca5b9811b08
Source noteuspto-grants-2010_12