HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Chloromethyl)-2-methyl-1,3-thiazole--hydrogen chloride (1/1) → HCID 11661667, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Chloromethyl)-2-methyl-1,3-thiazole--hydrogen chloride (1/1) | HCID 2734203 | — |
| Reactant | Methyl 2-fluoro-4-hydroxybenzoate | HCID 22463192 | — |
| Reactant | (R)-2-methyl-1-((S)-pyrrolidin-2-ylmethyl)pyrrolidine | HCID 46911921 | — |
| Product | HCID 11661667 | HCID 11661667 | — |
Reaction Steps
The title compound is prepared in a manner substantially analogous to Procedures D and E using 2-fluoro-4-hydroxy-benzoic acid methyl ester [CAS 197507-22-5], 4-chloromethyl-2-methylthiazole hydrochloride [CAS 39238-07-8], and 2-(R)-methyl-1-(2-(S)-pyrrolidinylmethyl)pyrrolidine. MS (ES+) m/e 418.2
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07846950B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-4a09f6778eef43389d463d5e059ab53f |
| Source note | uspto-grants-2010_12 |