HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 1-Benzyl-4-(chloromethyl)-1H-pyrazole--hydrogen chloride (1/1)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | (1-benzyl-1H-pyrazol-4-yl)methanol | HCID 16769828 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1-Benzyl-4-(chloromethyl)-1H-pyrazole--hydrogen chloride (1/1) | HCID 53422384 | — |
Reaction Steps
1.88 g of (1-benzyl-1H-pyrazol-4-yl)methanol was dissolved in 30 ml of dichloromethane, and 2.1 ml of thionyl chloride was added. The mixture was stirred at room temperature for 5 hours. The reaction mixture was concentrated under reduced pressure to obtain 2.39 g of 1-benzyl-4-(chloromethyl)-1H-pyrazole hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07846956B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-4a99bdcd3ffa489d9110a75bc35c9670 |
| Source note | uspto-grants-2010_12 |