HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 1-cyclohexyl-4-(chloromethyl)-1H-pyrazole hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | (1-cyclohexyl-1H-pyrazol-4-yl)methanol | HCID 57736379 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1-cyclohexyl-4-(chloromethyl)-1H-pyrazole hydrochloride | HCID 68777740 | — |
Reaction Steps
1.68 g of (1-cyclohexyl-1H-pyrazol-4-yl)methanol was dissolved in 20 ml of dichloromethane, and 2.0 ml of thionyl chloride was then added. The mixture was stirred at room temperature for 5 hours. The reaction mixture was concentrated under reduced pressure to obtain 2.15 g of 1-cyclohexyl-4-(chloromethyl)-1H-pyrazole hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07846956B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-728001e2b8f04767b2b31e542ca825ea |
| Source note | uspto-grants-2010_12 |