HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbon tetrabromide → HCID 57736292, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbon tetrabromide | HCID 11205 | — |
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | α-Methyl-5-(trifluoromethyl)-3-isoxazolemethanol | HCID 57736325 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 57736292 | HCID 57736292 | — |
Reaction Steps
1-(5-Trifluoromethyl-isoxazol-3-yl)ethanol was dissolved in 35 ml of diethyl ether, and 2.93 g of triphenylphosphine and 3.71 g of carbon tetrabromide were then added. The mixture was stirred at room temperature for 1 hour. The reaction mixture was subjected to silica gel column chromatography to obtain 1.14 g of 3-(1-bromoethyl)-5-trifluoromethylisoxazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07846956B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-2768f0ddf8164d5f920c87efd610098f |
| Source note | uspto-grants-2010_12 |