Carbon tetrabromide → HCID 57736348, compound

Participants

Reaction Steps

1.63 g of 1-(5-trifluoromethyl-isoxazol-3-yl)propanol was dissolved in 45 ml of diethyl ether, and 4.20 g of triphenylphosphine and 5.31 g of carbon tetrabromide were then added. The mixture was stirred at room temperature for 1 hour. The reaction mixture was subjected to silica gel column chromatography to obtain 1.00 g of 3-(1-bromopropyl)-5-trifluoromethylisoxazole.

Provenance & Evidence