[5-(Propan-2-yl)-1,2-oxazol-3-yl]methanol → 5-isopropylisoxazole-3-carbaldehyde

Participants

Reaction Steps

7.59 g of (5-i-propyl-isoxazol-3-yl)methanol was dissolved in 100 ml of 1,4-dioxane, and 21.74 g of manganese dioxide was then added. The mixture was stirred and heated under reflux for 10 hours. The reaction mixture was cooled to room temperature and then filtered through Celite®. The filtrate was concentrated under reduced pressure to obtain 6.72 g of 5-i-propyl-isoxazole-3-carbaldehyde.

Provenance & Evidence