Malononitrile → {[5-(1-Hydroxy-1-methylethyl)-isoxazol-3-yl]methylidene}malononitrile

関与物質

反応手順

4.63 g of 5-(1-hydroxy-1-methylethyl)isoxazole-3-carbaldehyde was dissolved in 50 ml of ethanol, and 1.98 g of malononitrile was then added. The mixture was stirred at room temperature for 5 hours. The reaction mixture was concentrated under reduced pressure, and the residue was subjected to silica gel column chromatography to obtain 5.35 g of {[5-(1-hydroxy-1-methylethyl)-isoxazol-3-yl]methylidene}malononitrile.

情報源と証拠