Ethanol → HCID 86631049, compound

HRID 2261366Notes

Reaction equation

HRID 2261366 reaction equation
[CH2:1]([S:3][C:4]1[N:5]([CH3:11])[C:6](C=O)=[CH:7][N:8]=1)[CH3:2].[C:12](#[N:16])[CH2:13][C:14]#[N:15].[CH2:17](O)C>>[CH2:1]([S:3][CH:4]1[N:5]([CH:11]=[C:13]([C:12]#[N:16])[C:14]#[N:15])[CH:6]=[CH:7][N:8]1[CH3:17])[CH3:2]

Participants

4

Reactant 3

HCID 702EthanolHCID 8010MalononitrileHCID 27633102-ethylthio-1-methylimidazole-5-carbaldehyde

Product 1

HCID 86631049HCID 86631049, compound

Procedure

5.13 g of 2-ethylthio-1-methylimidazole-5-carbaldehyde was dissolved in 30 ml of ethanol, and 2.00 g of malononitrile was then added. The mixture was stirred at room temperature for 3 hours. The reaction mixture was concentrated under reduced pressure. The residue was subjected to silica gel column chromatography to obtain 2.51 g of [(2-ethylthio-1-methylimidazol-3-yl)methylidene]malononitrile.

Workup

  1. concentrationThe reaction mixture was concentrated under reduced pressure

Sources & evidence

ORD record
ord-d071acc5f2a64e3d978898df9886a5ba
Source dataset
uspto-grants-2010_12
Patent number
US07846956B2

Reaction notes

Loading…