反应详情

温度

-78 °C

A 0.45 ml (5 mmole) of isobutyronitrile (Tokyo Kasei Co., Ltd.) was dissolved in 5 ml of THF, and the mixture was chilled to −78° C. under nitrogen atmosphere. Thereto was slowly added dropwise lithium diisopropylamine obtained above. The reaction mixture was stirred at −78° C. for 10 minutes and then heated to 0° C. Thereto was added dropwise a solution of 2.223 g (5 mmole) of diphenylbismuthanyl bromide prepared in Preparation Example 3 in 5 ml of THF.

1. customobtained above
2. temperatureheated to 0° C