反应详情

温度

70 °C

4-Nitro-1H-pyrrolo[2,3-b]pyridine 7-oxide 508 is prepared by dissolving 1H-Pyrrolo[2,3-b]pyridine 7-oxide 507 in nitric acid, followed by the addition of sulfuric acid. Heating (e.g. 70° C.) for one hour, followed by pouring into water provides compound 508, which is isolated by filtration. (Schneller et. al., J. Org. Chem. 1980, 45:4045)

1. custom4-Nitro-1H-pyrrolo[2,3-b]pyridine 7-oxide 508 is prepared