Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | HCID 178526243 | HCID 178526243 | — |
| Product | HCID 178526747 | HCID 178526747 | — |
Reaction Steps
4-Nitro-1H-pyrrolo[2,3-b]pyridine 7-oxide 508 is prepared by dissolving 1H-Pyrrolo[2,3-b]pyridine 7-oxide 507 in nitric acid, followed by the addition of sulfuric acid. Heating (e.g. 70° C.) for one hour, followed by pouring into water provides compound 508, which is isolated by filtration. (Schneller et. al., J. Org. Chem. 1980, 45:4045)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07846941B2 |
|---|
| Source dataset | uspto-grants-2010_12 |
|---|
| ORD ID | ord-89e97935a07a4d999ed51654807ba43f |
|---|
| Source note | uspto-grants-2010_12 |
|---|
