Methyl 4-methoxy-2-methylbenzoate → Methyl 4-hydroxy-2-methylbenzoate

HRID 2261783Notes

Reaction equation

HRID 2261783 reaction equation
COC(=O)C1C=C(O)C=CC=1CCC.[CH3:15][O:16][C:17](=[O:27])[C:18]1[CH:23]=[CH:22][C:21]([O:24]C)=[CH:20][C:19]=1[CH3:26]>>[CH3:15][O:16][C:17](=[O:27])[C:18]1[CH:23]=[CH:22][C:21]([OH:24])=[CH:20][C:19]=1[CH3:26]

Participants

3

Reactant 2

HCID 13257269Methyl 4-methoxy-2-methylbenzoateHCID 57443304HCID 57443304, compound

Product 1

HCID 12351986Methyl 4-hydroxy-2-methylbenzoateYield 77%

Procedure

The title compound (77%) is prepared essentially according to the preparation of 5-hydroxy-2-propyl-benzoic acid methyl ester using 4-methoxy-2-methyl-benzoic acid methyl ester. 1H NMR (400 MHz, CDCl3) δ 7.91-7.86 (m, 1H), 6.72-6.67 (m, 2H), 3.86 (s, 3H), 2.57 (s, 3H).

Sources & evidence

ORD record
ord-4dc682541de245f98e0ec8773c14bce9
Source dataset
uspto-grants-2010_12
Patent number
US07846960B2

Reaction notes

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