Thionyl Chloride → HCID 57179628, compound

HRID 2262340Notes

Reaction equation

HRID 2262340 reaction equation
S(Cl)(Cl)=O.[C:5]([NH:18][C@H:19]([C:25]([OH:27])=[O:26])[CH2:20][CH2:21][C:22]([OH:24])=[O:23])(=[O:17])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]>C(O)(C)C>[C:5]([NH:18][C@H:19]([C:25]([O:27][CH:9]([CH3:10])[CH3:8])=[O:26])[CH2:20][CH2:21][C:22]([O:24][CH:6]([CH3:7])[CH3:5])=[O:23])(=[O:17])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 93133N-Lauroyl-L-glutamic acid

Product 1

HCID 57179628HCID 57179628, compoundYield 195.3%

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

7.24 g of thionyl chloride was gradually and dropwise added to 73.32 g of isopropyl alcohol, then 10.0 g of N-lauroylglutamic acid was added, and reacted at room temperature for 1 day. The reaction liquid was concentrated under reduced pressure to obtain 12.26 g of a white crystal of diisopropyl N-lauroylglutamate.

Workup

  1. customreacted at room temperature for 1 day
  2. customThe reaction liquid
  3. concentrationwas concentrated under reduced pressure

Sources & evidence

ORD record
ord-7bd29585c81947e59e49af2eccf5c91d
Source dataset
uspto-grants-2010_12
Patent number
US07850955B2

Reaction notes

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