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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2262539Generated: October 30, 2026

Cyclopropylamine → HCID 25131101, compound

https://huagongshe.com/reaction/2262539

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropylamineHCID 69828—
ReactantHCID 25130783HCID 25130783—
ProductHCID 25131101HCID 2513110127%

Reaction Steps

As described for Example 10, 4-[4-(3-phenyl-5-trifluoromethyl-isoxazol-4-yl)-imidazol-1-yl]-benzoic acid methyl ester (70 mg, 0.17 mmol) was converted, using cyclopropylamine instead of cyclopropanemethylamine, to the title compound (20 mg, 27%) which was obtained as a white solid. MS: m/e=439.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07851469B2
Source datasetuspto-grants-2010_12
ORD IDord-d5088a3122524394a9051bc17a61660c
Source noteuspto-grants-2010_12