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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2262545Generated: November 2, 2026

HCID 25130783, compound → HCID 25132478, compound

https://huagongshe.com/reaction/2262545

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 25130783HCID 25130783—
ReactantHCID 25132124HCID 25132124—
ProductHCID 25132478HCID 2513247851%

Reaction Steps

As described for Example 10, 6-[4-(3-phenyl-5-trifluoromethyl-isoxazol-4-yl)-imidazol-1-yl]-nicotinic acid methyl ester (90 mg, 0.22 mmol), instead of 4-[4-(3-phenyl-5-trifluoromethyl-isoxazol-4-yl)-imidazol-1-yl]-benzoic acid methyl ester was converted, to the title compound (50 mg, 51%) which was obtained as a white solid. MS: m/e=454.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07851469B2
Source datasetuspto-grants-2010_12
ORD IDord-370e2e4e46854e16b8b6358c68cb4d0c
Source noteuspto-grants-2010_12