HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → HCID 25132482, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | HCID 25132124 | HCID 25132124 | — |
| Product | HCID 25132482 | HCID 25132482 | 28% |
Reaction Steps
As described for Example 18, 6-[4-(3-phenyl-5-trifluoromethyl-isoxazol-4-yl)-imidazol-1-yl]-nicotinic acid methyl ester (90 mg, 0.22 mmol), was converted, using morpholine instead of cyclopropanemethylamine, to the title compound (28 mg, 28%) which was obtained as a yellow oil. MS: m/e=470.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07851469B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-9666919570464c3b8f03528bd6cd8780 |
| Source note | uspto-grants-2010_12 |