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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2262580Generated: November 2, 2026

HCID 25130783, compound → HCID 25133158, compound

https://huagongshe.com/reaction/2262580

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 25130783HCID 25130783—
ReactantHCID 67361949HCID 67361949—
ProductHCID 25133158HCID 2513315883%

Reaction Steps

As described for Example 10, 6-{4-[3-(4-chloro-phenyl)-5-trifluoromethyl-isoxazol-4-yl]-imidazol-1-yl}-nicotinic acid methyl ester (100 mg, 0.23 mmol), instead of 4-[4-(3-phenyl-5-trifluoromethyl-isoxazol-4-yl)-imidazol-1-yl]-benzoic acid methyl ester was converted, to the title compound (90 mg, 83%) which was obtained as a white solid. MS: m/e=488.1 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07851469B2
Source datasetuspto-grants-2010_12
ORD IDord-ce37ebadc8ca4e06a0d598f7b3464351
Source noteuspto-grants-2010_12