HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 25130783, compound → HCID 25133158, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 25130783 | HCID 25130783 | — |
| Reactant | HCID 67361949 | HCID 67361949 | — |
| Product | HCID 25133158 | HCID 25133158 | 83% |
Reaction Steps
As described for Example 10, 6-{4-[3-(4-chloro-phenyl)-5-trifluoromethyl-isoxazol-4-yl]-imidazol-1-yl}-nicotinic acid methyl ester (100 mg, 0.23 mmol), instead of 4-[4-(3-phenyl-5-trifluoromethyl-isoxazol-4-yl)-imidazol-1-yl]-benzoic acid methyl ester was converted, to the title compound (90 mg, 83%) which was obtained as a white solid. MS: m/e=488.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07851469B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-ce37ebadc8ca4e06a0d598f7b3464351 |
| Source note | uspto-grants-2010_12 |