Sodium Hydroxide → HCID 68777897, compound

Participants

Reaction Steps

1-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]piperidine hydrochloride (1.00 g, 2.99 mmol) was dissolved in water. The solution was neutralized with 1N aqueous sodium hydroxide solution, and the mixture was extracted with chloroform. The extract was washed with water and dried over magnesium sulfate anhydrous, and the solvent was distilled off under reduced pressure to give the desired product (772 mg, 98.4 mmol) as an oil.

Provenance & Evidence