Triethylamine → HCID 59594488, compound

Participants

Reaction Steps

To a solution of 1-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine (246 mg, 1.00 mmol) and triethylamine (0.139 ml, 1.00 mmol) in tetrahydrofuran (6 ml) was added 3-pyridylisothiocyanate (0.167 ml, 1.50 mmol), the mixture was stirred at room temperature for 3 hours and the solvent was distilled off under reduced pressure. The residue was recrystallized from a mixed solvent of tetrahydrofuran and ethyl acetate to obtain the desired product (233 mg, 61.0%) as a solid.

Provenance & Evidence