3-Methoxyacetophenone → Bromomethyl 3-methoxyphenyl ketone

Participants

Reaction Steps

Bromine (5.32 g, 33.3 mmol) was slowly added dropwise to a solution of 1-(3-methoxyphenyl)ethanone (5.00 g, 33.3 mmol) in diethyl ether (100 ml), and the mixture was stirred at room temperature for 4 hours. The reaction mixture was distilled off under reduced pressure to give the desired product as an oil quantitatively.

Provenance & Evidence