Water → 2-Oxo-2-[3-(trifluoromethyl)phenyl]ethyl thiocyanate

Participants

Reaction Steps

A solution of 2-bromo-1-[3-(trifluoromethyl)phenyl]ethanone (7.10 g, 26.6 mmol) and potassium thiocyanate (2.58 g, 26.6 mmol) in ethanol (70 ml) was stirred at 80° C. for 2 hours. After cooling to room temperature, water (70 ml) was poured to the reaction mixture, and crystals were collected by filtration, and washed with water to give 3.88 g (59.5%) of the desired product as a solid.

Provenance & Evidence