Water → HCID 68780326, compound

HRID 2263314Notes

Reaction equation

HRID 2263314 reaction equation
[BrH:1].C(O)(=O)C.[Cl:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[C:13](=O)[CH2:14][S:15][C:16]#[N:17].O>C(O)(=O)C>[Br:1][C:16]1[S:15][CH:14]=[C:13]([C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[Cl:6])[N:17]=1

Participants

5

Reactant 3

HCID 962WaterHCID 21893785Acetic Acid Mixture with Hydrobromic AcidHCID 242137572-(2-Chlorophenyl)-2-oxoethyl thiocyanate

Product 1

HCID 68780326HCID 68780326, compoundYield 67.1%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Conditions

Temperature
130 °C

Procedure

A 25% hydrogen bromide/acetic acid (50 ml) solution was added to a solution of 2-(2-chlorophenyl)-2-oxoethyl thiocyanate (5.15 g, 24.3 mmol) in acetic acid (50 ml), and the mixture was stirred at 130° C. for 2 hours. Water (100 ml) was poured to the reaction mixture, and crystals were collected by filtration and washed with water to give 4.48 g (67.1%) of the desired product as a solid.

Workup

  1. filtrationwere collected by filtration
  2. washwashed with water

Sources & evidence

ORD record
ord-2f701d08443a4b278a87953a1468c993
Source dataset
uspto-grants-2010_12
Patent number
US07851473B2

Reaction notes

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