Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Acetic Acid Mixture with Hydrobromic Acid | HCID 21893785 | — |
| Reactant | 2-(2-Chlorophenyl)-2-oxoethyl thiocyanate | HCID 24213757 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 68780326 | HCID 68780326 | 67.1% |
Reaction Steps
A 25% hydrogen bromide/acetic acid (50 ml) solution was added to a solution of 2-(2-chlorophenyl)-2-oxoethyl thiocyanate (5.15 g, 24.3 mmol) in acetic acid (50 ml), and the mixture was stirred at 130° C. for 2 hours. Water (100 ml) was poured to the reaction mixture, and crystals were collected by filtration and washed with water to give 4.48 g (67.1%) of the desired product as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07851473B2 |
|---|
| Source dataset | uspto-grants-2010_12 |
|---|
| ORD ID | ord-2f701d08443a4b278a87953a1468c993 |
|---|
| Source note | uspto-grants-2010_12 |
|---|
