Hydrochloric Acid → HCID 11536246, compound

Participants

Reaction Steps

Preparation according to Example 2: 4-[2-fluoro-3-(trifluoromethyl)phenyl]-1-methyl-1,2,3,6-tetrahydropyridine (0.59 g, 2.28 mmol), methanol (30 ml), palladium on carbon (0.07 g) and hydrochloric acid (0.1 ml, conc). Yield: 0.43 g. The amine was converted to the hydrochloric acid salt and recrystallized from ethanol/diethyl ether: M.p. 260-261° C. MS m/z (relative intensity, 70 eV) 261 (M+, 69), 260 (bp), 242 (9), 97 (12) 70 (37).

Provenance & Evidence